Imprint Cytology of Gastric Mucosa Biopsy – Fast, Simple and Reliable Method for Detection of Helicobacter Pylori InfectionReport as inadecuate




Imprint Cytology of Gastric Mucosa Biopsy – Fast, Simple and Reliable Method for Detection of Helicobacter Pylori Infection - Download this document for free, or read online. Document in PDF available to download.

Collegium antropologicum, Vol.32 No.1 May 2008. -

The aim of the study was to determine the value of gastric mucosa imprint cytology in the detection of Helicobacter

pylori infection. A total of 182 biopsy specimens, from 182 randomly selected patients undergoing gastroscopy with gastric

mucosa biopsy, were analyzed. Specimens were first submitted to slide imprinting and then formalin fixed for further

routine histopathology. One-hundred and fifty-five specimens proved adequate for definitive comparison of the methods

used for detection of Helicobacter pylori infection. Helicobacter pylori was detected by histopathology in 51 specimens

and by cytology in 54 specimens. Agreement between the findings obtained by the two methods was recorded in 130 of 155

83.1% specimens. Positive cytology and negative histology findings were obtained in 14, and vice versa in 11 specimens.

Gastric mucosa imprint cytology provides a useful method for the detection of Helicobacter pylori infection. The method

is advantageous for being fast, simple and inexpensive. When the sample is obtained exclusively for confirmation of the

presence of Helicobacter pylori infection, cytology reduces the time and cost of the procedure, at the same time providing

data on morphological changes of gastric mucosa. Every finding suspect of malignant transformation of the mucosa can

also be verified by histopathology because imprint manipulation causes no damage to the sample.

imprint cytology; Helicobacter pylori; gastric mucosa biopsy



Author: Ivana Knežević Štromar - Jasminka Jakić-Razumović - Anka Knežević-Obad -

Source: http://hrcak.srce.hr/



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