Sickle Cell Disease and Pregnancy: Does Outcome Depend on Genotype or PhenotypeReport as inadecuate




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Objective: Women with Sickle Cell Disease SCD who become pregnant are at risk for serious maternal and fetal complications. Our objective was to determine if pregnancy outcome is dependent on phenotype. Methods: Retrospective cohort study of pregnant women with SCD, including hemoglobin Hb SS, Hb SC, and Hb Sβ-thalassemia, between January 1999 and December 2008. Antenatal and neonatal outcomes were compared between pregnancies with painful episodes and those without. The primary outcome was preterm birth PTB



Author: Catherine Berzolla, Neil S Seligman, Aisha Nnoli, Kevin Dysart, Jason K Baxter, Samir K Ballas

Source: http://www.scirp.org/



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