Bone T-Scores and Functional Status: A Cross-Sectional Study on German ElderlyReport as inadecuate




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Background

We explore the association between bone T-scores, used in osteoporosis diagnosis, and functional status since we hypothesized that bone health can impact elderly functional status and indirectly independence.

Methods

In a cross-sectional study 2005–2006 on community dwelling elderly > = 75 years from Herne, Germany we measured bone T-scores with Dual-energy X-ray Absorptiometry, and functional status indexed by five geriatric tests: activities of daily living, instrumental activities of daily living, test of dementia, geriatric depression score and the timed-up-and-go test, and two pooled indexes: raw and standardized. Generalized linear regression was used to determine the relationship between T-scores and functional status.

Results

From 3243 addresses, only 632 19% completed a clinical visit, of which only 440 male∶female, 243∶197 could be included in analysis. T-scores −0.99, 95% confidence interval CI, −1.1–0.9 predicted activities of daily living 95.3 CI, 94.5–96.2, instrumental activities of daily living 7.3 CI, 94.5–96.2, and timed-up-and-go test 10.7 CI, 10.0–11.3 P< = 0.05. Pooled data showed that a unit improvement in T-score improved standardized pooled functional status 15 CI, 14.7–15.3 by 0.41 and the raw 99.4 CI, 97.8–101.0 by 2.27 units. These results were limited due to pooling of different scoring directions, selection bias, and a need to follow-up with evidence testing.

Conclusions

T-scores associated with lower functional status in community-dwelling elderly. Regular screening of osteoporosis as a preventive strategy might help maintain life quality with aging.



Author: Shoma Berkemeyer , Jochen Schumacher, Ulrich Thiem, Ludger Pientka

Source: http://plos.srce.hr/



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