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Vegetable oil was successfully used as solvent and acyl donor in the kinetic resolution of several secondary alcohol racemates yielding high enantioselectivities. Using vegetable oil as solvent and acyl donor allowed easy separation of the pure alcohol enantiomer by extraction with methanol, by distillation under reduced pressure, or by column chromatography.


Oil, Kinetic Resolution, Lipase, Separation

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A. Wolfson, N. Komyagina, C. Dlugy and J. Blumenfeld -Resolution of Alcohol Racemate by Oil,- Green and Sustainable Chemistry, Vol. 1 No. 1, 2011, pp. 7-11. doi: 10.4236-gsc.2011.11002.

Author: Adi Wolfson, Nadia Komyagina, Christina Dlugy, Janine Blumenfeld



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