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Collegium antropologicum, Vol.24 No.2 December 2000. -

The difference of test results between patients with »pure« atopic dermatitis AD and »mixed« AD with concomitant respiratory allergy, RA was investigated in 30 AD patients. The results showed the onset of disease that mostly occur in the early infancy 15 50% patients had developed the disease under the age of 2 – 2-10 in »pure« AD, and 13-20 in »mixed« AD . Twenty 66.6% of them had a history of RA »mixed« AD whereas the remaining 10 33.3% had »pure« AD. Seventeen 56.6% AD patients had one concomitant allergic disease, while 3 10% patients had two comorhid conditions AR and AB each. Family history was positive for atopy in 22 73.3% AD patients in 14 46.6% patients in a first-degree relative . Twenty-four 80% patients had positive prick test 9-10 90% in »pure« AD and 15-20 75% in »mixed« AD, mostly for house dust 20. Positive scratch test was observed in 16 53.3% patients 4-10 in »pure« AD, and 12-20 in »mixed« AD . Nineteen 63.3% AD patients showed positive patch test reaction 5-10 in »pure« AD, and 14-20 in »mixed« AD. AD patients had higher serum IgE 21-30 than non-atopic ones but similar in »pure« AD, and »mixed« AD 7-10 70% in »pure« AD, and 14-20 70% in »mixed« AD . Determination of CD23 marker on B-lymphocytes showed normal values in 24, and increased values in six patients 2-10 in »pure« AD, and 4-20 in »mixed« AD. The values of CD21 were decreased in 16 AD patients 6-10 in »pure« AD, and 10-20 in »mixed« AD. HLA-DR expression was normal in almost all patients. There were no statistically significant differences p



Author: L. Lugović - J. Lipozenčić -

Source: http://hrcak.srce.hr/



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