The Broad Host Range and Genetic Diversity of Mammalian and Avian AstrovirusesReport as inadecuate


The Broad Host Range and Genetic Diversity of Mammalian and Avian Astroviruses


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1

Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia

2

Duke-NUS Medical School, Singapore 169857, Singapore





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Author to whom correspondence should be addressed.



Academic Editor: Stacey Schultz-Cherry

Abstract Astroviruses are a diverse family of viruses that infect a wide range of mammalian and avian hosts. Here we describe the phylogenetic diversity and current classification methodology of astroviruses based on the ORF1b and ORF2 genes, highlighting the propensity of astroviruses to undergo interspecies transmission and genetic recombination which greatly increase diversity and complicate attempts at a unified and comprehensive classification strategy. View Full-Text

Keywords: astrovirus; classification; avian; mammal; genetic diversity; capsid; RNA-dependent-RNA-polymerase; ORF1b; ORF2 astrovirus; classification; avian; mammal; genetic diversity; capsid; RNA-dependent-RNA-polymerase; ORF1b; ORF2





Author: Celeste Donato 1 and Dhanasekaran Vijaykrishna 1,2,*

Source: http://mdpi.com/



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