Ion Selective PVC Membrane Electrode for the Determination of Methacycline Hydrochloride in Pharmaceutical FormulationReport as inadecuate


Ion Selective PVC Membrane Electrode for the Determination of Methacycline Hydrochloride in Pharmaceutical Formulation


Ion Selective PVC Membrane Electrode for the Determination of Methacycline Hydrochloride in Pharmaceutical Formulation - Download this document for free, or read online. Document in PDF available to download.

1

Pharmaceutical Analysis Laboratory Biological and Medical Research Department, MBC-03-65, King Faisal Specialist Hospital & Research Center, P.O. Box 3354, Riyadh 11211, Saudi Arabia

2

Department of Chemical Engineering, Jiangsu Institute of Petrochemical Technology, Changzhou 213016, Peoples Republic of China

3

P.O. Box 1048, Beijing 102205, Peoples Republic of China





*

Author to whom correspondence should be addressed.



Abstract A plastic membrane electrode for the determination of methacycline hydrochloride was fabricated based on the use of methacycline-tetraphenylborate as the electroactive substance, and dioctylphtalate as the plasticizing agent. It was found that the potential responses of the electrode were influenced by pH of the tested solution when pH3. Under the condition of pH 2.6, the linear response range, slope 25ºC and detection limit obtained were 3.0×10-2~6.0×10-6M, 52.9mv per decade and 3.4×10-6M ,respectively. The response time of the electrodes was



Author: Hassan Y. Aboul-Enein 1,* , Xian Xiang Sun 2 and Cheng Jun Sun 3

Source: http://mdpi.com/



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