Reagents for Lithium Electrodes and Sensors for Blood Serum AnalysisReport as inadecuate




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Department of Chemistry, Box 351700, University of Washington, Seattle, WA 98195-1700, USA





Abstract The measurement of lithium in blood serum requires high selectivity since the blood contains about 140 mM sodium compared to the 0.5-1.5 mM lithium level in manic depressive patients under treatment with lithium salts. This review traces the development of optical and potentiometric methods for the selective measurement of lithium in the presence of sodium. Selectivities of over 1,000:1 are achievable with properly designed ionophores.

Keywords: Spectrophotometry; Fluorescence; Sensors; Ion-Selective Electrodes; Crown Ethers; Cryptands; Diamide Ionophores Spectrophotometry; Fluorescence; Sensors; Ion-Selective Electrodes; Crown Ethers; Cryptands; Diamide Ionophores





Author: Gary D. Christian

Source: http://mdpi.com/



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