Indirubine-3-Monoxime Inhibits PDGF-Mediated Vascular Smooth Muscle Cell MigrationReport as inadecuate




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Department of Pharmacognosy, University of Vienna, Althanstr. 14, 1090, Vienna, Austria





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Abstract During the pathology of atherosclerosis and restenosis, hyperproliferation and migration of vascular smooth muscle cells VSMC contribute to lumen loss of the vessel and neointima formation 1. Drugs interfering with both, proliferation and migration of VSMC are therefore promising candidates for the treatment of vasculoproliferative diseases.





Author: I. SROKA * , E. H. HEISS, C. CZALOUN and V. M. DIRSCH

Source: http://mdpi.com/



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