NF-κB Inhibitory Activities of the Methanol Extracts and some Constituents therein of some Vietnamese Medicinal PlantsReport as inadecuate




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1

Department of Pharmaceutical Chemistry, Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Vietnam

2

Department of Chemistry, University of South Dakota, South Dakota, USA





*

Author to whom correspondence should be addressed.



Abstract Eighty-seven methanol extracts of medicinal plants, most of them are currently used in Vietnamese oriental medicine, were screened for NF-κB inhibitory activity. Seven methanol extracts showed strong to moderate inhibitory activity. These include the extracts of Crinum latifolium leaves, Evodia rutaecarpa fruits, Polygonum cuspidatum rhizoma, Perilla ocymoides leaves, Rubia cordifolia leaves, Scutellaria barbata leaves and Sparganium stenophyllum leaves. The NF-κB inhibitory activities of several metabolites isolated from some of these plants were also reported.

Keywords: NF-κB Inhibitory Activity; Screening; Medicinal Plants NF-κB Inhibitory Activity; Screening; Medicinal Plants





Author: Nguyen H. NAM 1,* and You Y. JAE 2

Source: http://mdpi.com/



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