Layer-by-Layer Self-Assembling Gold Nanorods and Glucose Oxidase onto Carbon Nanotubes Functionalized Sol-Gel Matrix for an Amperometric Glucose BiosensorReport as inadecuate


Layer-by-Layer Self-Assembling Gold Nanorods and Glucose Oxidase onto Carbon Nanotubes Functionalized Sol-Gel Matrix for an Amperometric Glucose Biosensor


Layer-by-Layer Self-Assembling Gold Nanorods and Glucose Oxidase onto Carbon Nanotubes Functionalized Sol-Gel Matrix for an Amperometric Glucose Biosensor - Download this document for free, or read online. Document in PDF available to download.

1

MOE Key Laboratory of Laser Life Science and Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou 510631, China

2

School of Electronic and Information Engineering, South China University of Technology, Guangzhou 510640, China

3

The key Laboratory of Bioactive Materials Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China





*

Author to whom correspondence should be addressed.



Academic Editor: Ming Su

Abstract A novel amperometric glucose biosensor was fabricated by layer-by-layer self-assembly of gold nanorods AuNRs and glucose oxidase GOD onto single-walled carbon nanotubes SWCNTs-functionalized three-dimensional sol-gel matrix. A thiolated aqueous silica sol containing SWCNTs was first assembled on the surface of a cleaned Au electrode, and then the alternate self-assembly of AuNRs and GOD were repeated to assemble multilayer films of AuNRs-GOD onto SWCNTs-functionalized silica gel for optimizing the biosensor. Among the resulting glucose biosensors, the four layers of AuNRs-GOD-modified electrode showed the best performance. The sol-SWCNTs-AuNRs- GOD4-Au biosensor exhibited a good linear range of 0.01–8 mM glucose, high sensitivity of 1.08 μA-mM, and fast amperometric response within 4 s. The good performance of the proposed glucose biosensor could be mainly attributed to the advantages of the three-dimensional sol-gel matrix and stereo self-assembly films, and the natural features of one-dimensional nanostructure SWCNTs and AuNRs. This study may provide a new facile way to fabricate the enzyme-based biosensor with high performance. View Full-Text

Keywords: biosensor; layer-by-layer; sol-gel; gold nanorods AuNRs; carbon nanotubes biosensor; layer-by-layer; sol-gel; gold nanorods AuNRs; carbon nanotubes





Author: Baoyan Wu 1, Shihua Hou 2,* , Zhiying Miao 3, Cong Zhang 3 and Yanhong Ji 1

Source: http://mdpi.com/



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