Improvement of a Critical Intermediate Step in the Synthesis of a Nitroxide-Based Spin-Labeled Deoxythymidine AnalogReport as inadecuate




Improvement of a Critical Intermediate Step in the Synthesis of a Nitroxide-Based Spin-Labeled Deoxythymidine Analog - Download this document for free, or read online. Document in PDF available to download.

Department of Basic Pharmaceutical Sciences, West Virginia University School of Pharmacy, P. O. Box 9530, Morgantown, West Virginia, USA





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Abstract Methods to reduce the carboxylic acid moiety in 3-carboxy-2,2,5,5-tetramethylpyrrolin-1-oxyl to an alcohol as an intermediate toward the corresponding aldehyde have been explored and an improved method has been developed. View Full-Text

Keywords: Nitroxide; spin label; reduction; carboxylic acid; alcohol; anhydride Nitroxide; spin label; reduction; carboxylic acid; alcohol; anhydride





Author: Jeannine H. Powell, Edward M. Johnson, II and Peter M. Gannett *

Source: http://mdpi.com/



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