Microwave-Assisted One-Pot Synthesis of Pyrazolone Derivatives under Solvent-Free ConditionsReport as inadecuate




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1

School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China

2

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China

3

Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China





*

Authors to whom correspondence should be addressed.



Abstract An efficient one-pot method to generate structurally diverse and medicinally interesting pyrazolone derivatives in good to excellent yields of 51–98% under microwave irradiation and solvent-free conditions has been developed.

Keywords: microwave-assisted reactions; one-pot; pyrazolones microwave-assisted reactions; one-pot; pyrazolones





Author: Ruoqun Ma 1, Jin Zhu 1, Jie Liu 1, Lili Chen 2,* , Xu Shen 1,2, Hualiang Jiang 1,2,3 and Jian Li 1,2,*

Source: http://mdpi.com/



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