Steroidal and Phenolic Glycosides from the Bulbs of Lilium pumilum DC and Their Potential Na -K ATPase Inhibitory ActivityReport as inadecuate




Steroidal and Phenolic Glycosides from the Bulbs of Lilium pumilum DC and Their Potential Na -K ATPase Inhibitory Activity - Download this document for free, or read online. Document in PDF available to download.

1

Chemistry Science and Technology School, Zhanjiang Normal University, 29 Cunjin Road, Zhanjiang 524048, China

2

Development Center for New Materials Engineering Technology in Universities of Guangdong, Zhanjiang Normal University, 29 Cunjin Road, Zhanjiang 524048, China

3

Department of Pharmacy, Shaoyang Medical College Level Speciaity School, 18 Baoqing Road, Shaoyang 422000, China





*

Author to whom correspondence should be addressed.



Abstract A new steroidal saponin, named pumilum A 1, and a new phenolic glycoside, threo-1-4′-hydroxy-2′-methoxyphenyl-2-2′′,4′′-dihydroxyphenyl-1,3-propanediol-4′-O-β-D-glucopyranoside 7 were isolated from the methanolic extract of the bulbs of Lilium pumilum DC, along with five known steroidal saponins. Their chemical structures were elucidated on the basis of detailed spectroscopic analysis, including 1D and 2D NMR techniques and chemical methods. In addition, the inhibitory activity of all the isolates on Na+-K+ ATPase was evaluated.

Keywords: Lilium pumilum DC; pumilum A; Na+-K+ ATPase Lilium pumilum DC; pumilum A; Na+-K+ ATPase





Author: Zhong-Liu Zhou 1,* , Zong-Cai Feng 2, Chun-Yan Fu 3, Hua-Lin Zhang 1 and Jing-Min Xia 1

Source: http://mdpi.com/



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