Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their BioactivitiesReport as inadecuate




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1

College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China

2

College of Science, China Agricultural University, Beijing 100193, China





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Authors to whom correspondence should be addressed.



Abstract The endophytic fungus Hyalodendriella sp. Ponipodef12 was isolated from the hybrid ‘Neva’ of Populus deltoides Marsh × P. nigra L. In this study, four benzopyranones were isolated from the ethyl acetate extract of Hyalodendriella sp. Ponipodef12, and identified as palmariol B 1, 4-hydroxymellein 2, alternariol 9-methyl ether 3, and botrallin 4 by means of physicochemical and spectroscopic analysis. All the compounds were evaluated for their antibacterial, antifungal, antinematodal and acetylcholinesterase inhibitory activities. 4-Hydroxymellein 2 exhibited stronger antibacterial activity than the other compounds. Palmariol B 1 showed stronger antimicrobial, antinematodal and acetylcholinesterase inhibitory activities than alternariol 9-methyl ether 3 which indicated that the chlorine substitution at position 2 may contribute to its bioactivity. The results indicate the potential of this endophytic fungus as a source of bioactive benzopyranones.

Keywords: poplar hybrid ‘Neva’ endophytic fungus; Hyalodendriella sp. Ponipodef12; benzopyranones; palmariol B; 4-hydroxymellein; alternariol 9-methyl ether; botrallin; bioactivities poplar hybrid ‘Neva’ endophytic fungus; Hyalodendriella sp. Ponipodef12; benzopyranones; palmariol B; 4-hydroxymellein; alternariol 9-methyl ether; botrallin; bioactivities





Author: Xiangjie Meng 1, Ziling Mao 1, Jingfeng Lou 1, Liang Xu 1, Lingyun Zhong 1, Youliang Peng 1, Ligang Zhou 1,* and Mingan Wang 2,*

Source: http://mdpi.com/



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