A Metabolomic Approach for the Discrimination of Red Ginseng Root Parts and Targeted ValidationReport as inadecuate


A Metabolomic Approach for the Discrimination of Red Ginseng Root Parts and Targeted Validation


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Korea Ginseng Research Institute, Korea Ginseng Corporation, Daejeon 305-805, Korea





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Academic Editors: Woo-Sik Jeong, Anusha Chaparala and Lorne Hofseth

Abstract Ginsenosides are used as existing markers of red ginseng RG quality, and ginsenoside ratios are also indicative of the different components of red ginseng. For the analysis and classification of ginsenoside content, red ginseng was separated into three parts, namely, main roots, lateral roots, and fine roots, and each extract was subjected to ultra-performance liquid chromatography quadruple time-of-flight mass spectrometry UPLC-QToF-MS with multivariate statistical analysis. Principal component analysis PCA showed a clear discrimination between the extracts of main roots and fine roots and suggested discrimination markers four for the main roots and five for the fine roots. The fine root markers were identified as ginsenoside. We identified two markers for the main roots of red ginseng in this study. Moreover, the contents of 22 ginsenosides were analyzed in all three components of red ginseng. Fine roots have the highest protopanaxadiol PPD-protopanaxatriol PPT ratio. The PPD group of ginsenosides, which is quantitatively dominant in fine roots, clearly distinguishes the main roots from the other parts. View Full-Text

Keywords: Panax ginseng; red ginseng RG; metabolomics; ultra-performance liquid chromatography quadruple time-of-flight mass spectrometry UPLC-QToF-MS Panax ginseng; red ginseng RG; metabolomics; ultra-performance liquid chromatography quadruple time-of-flight mass spectrometry UPLC-QToF-MS





Author: Gyo In, Hyun Kyu Seo, Hee-Won Park and Kyoung Hwa Jang *

Source: http://mdpi.com/



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