N-2-7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzogpteridin-102H-ylethylidene-4-nitrobenzohydrazideReport as inadecuate


N-2-7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzogpteridin-102H-ylethylidene-4-nitrobenzohydrazide


N-2-7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzogpteridin-102H-ylethylidene-4-nitrobenzohydrazide - Download this document for free, or read online. Document in PDF available to download.

Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, Sanuki, Kagawa 769-2193, Japan





*

Author to whom correspondence should be addressed.



Abstract The title compound, N-2-7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzogpteridin- 102H-ylethylidene-4-nitrobenzohydrazide 1, was obtained by the reaction of formylmethylflavin and p-nitrobenzohydrazide. The product 1 inhibited the DNA binding of nuclear factor-κB, and was characterized by 1H-NMR, 13C-NMR, electrospray ionization mass spectrometry, elemental analysis, IR and UV. View Full-Text

Keywords: flavin; Nuclear factor-κB; inhibitor; DNA binding flavin; Nuclear factor-κB; inhibitor; DNA binding





Author: Masayuki Morikawa, Katsuhito Kino * , Eriko Asada, Kosuke Katagiri, Kanami Mori-Yasumoto, Masayo Suzuki, Takanobu Kobayashi and Hiroshi Miyazawa

Source: http://mdpi.com/



DOWNLOAD PDF




Related documents