Ultra-Portable Smartphone Controlled Integrated Digital Microfluidic System in a 3D-Printed Modular AssemblyReport as inadecuate




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School of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada





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Academic Editors: Andrew deMello and Xavier Casadevall i Solvas

Abstract Portable sensors and biomedical devices are influenced by the recent advances in microfluidics technologies, compact fabrication techniques, improved detection limits and enhanced analysis capabilities. This paper reports the development of an integrated ultraportable, low-cost, and modular digital microfluidic DMF system and its successful integration with a smartphone used as a high-level controller and post processing station. Low power and cost effective electronic circuits are designed to generate the high voltages required for DMF operations in both open and closed configurations from 100 to 800 V. The smartphone in turn commands a microcontroller that manipulate the voltage signals required for droplet actuation in the DMF chip and communicates wirelessly with the microcontroller via Bluetooth module. Moreover, the smartphone acts as a detection and image analysis station with an attached microscopic lens. The holder assembly is fabricated using three-dimensional 3D printing technology to facilitate rapid prototyping. The holder features a modular design that enables convenient attachment-detachment of a variety of DMF chips to-from an electrical busbar. The electrical circuits, controller and communication system are designed to minimize the power consumption in order to run the device on small lithium ion batteries. Successful controlled DMF operations and a basic colorimetric assay using the smartphone are demonstrated. View Full-Text

Keywords: digital microfluidics; biomedical devices; smartphone; 3D printing; high voltage circuits digital microfluidics; biomedical devices; smartphone; 3D printing; high voltage circuits





Author: Mohamed Yafia, Ali Ahmadi, Mina Hoorfar and Homayoun Najjaran *

Source: http://mdpi.com/



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