GC-MS Analysis and Preliminary Antimicrobial Activity of Albizia adianthifolia Schumach and Pterocarpus angolensis DCReport as inadecuate


GC-MS Analysis and Preliminary Antimicrobial Activity of Albizia adianthifolia Schumach and Pterocarpus angolensis DC


GC-MS Analysis and Preliminary Antimicrobial Activity of Albizia adianthifolia Schumach and Pterocarpus angolensis DC - Download this document for free, or read online. Document in PDF available to download.

Chemistry Department, University of Botswana, P-Bag 0022, Gaborone, Botswana





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Academic Editors: Lutfun Nahar, Norazah Basar and Satyajit D. Sarker

Abstract The non-polar components of two leguminoceae species Albizia adianthifolia Schumach, and Pterocarpus angolensis DC were investigated. GC-MS analysis of the crude n-hexane and chloroform extracts together with several chromatographic separation techniques led to the identification and characterization using NMR of sixteen known compounds from the heartwood and stem bark of Albizia adianthifolia and Pterocarpus angolensis respectively. These constituents include, n-hexadecanoic acid palmitic acid 1, oleic acid 2, chondrillasterol 3, stigmasterol 4, 24S 5α-stigmast-7-en-3β-ol 5, 9,12-octadecadienoic acid Z,Z-, methyl ester 6, trans-13-octadecanoic acid, methyl ester 7, tetradecanoic acid 8, hexadecanoic acid, methyl ester 9, octadecanoic acid 10, tetratriacontane 11, 7-dehydrodiosgenin 12, lupeol 13, stigmasta-3,5-diene-7-one 14, friedelan-3-one friedelin 15, and 1-octacosanol 16. Using agar over lay method, the preliminary antimicrobial assay for the extracts was carried out against bacterial E. coli, P. aeruginosa, B. subtilis, S. aueus and a fungus-yeast C. albicans strains. The n-hexane and chloroform extracts of A. adianthifolia showed the best activity against E. coli with minimum inhibition quantity MIQ of 1 µg each while the remaining exhibited moderate-to-weak activity against the test microorganisms. View Full-Text

Keywords: GC-MS; NMR; antimicrobial activity; A. adianthifolia; P. angolensis GC-MS; NMR; antimicrobial activity; A. adianthifolia; P. angolensis





Author: Mustapha N. Abubakar and Runner R. T. Majinda *

Source: http://mdpi.com/



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