Three New Cembranoids from the Taiwanese Soft Coral Sarcophyton ehrenbergiReport as inadecuate




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1

Asia-Pacific Ocean Research Center, National Sun Yat-Sen University, Kaohsiung 804, Taiwan

2

Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan

3

Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan





*

Author to whom correspondence should be addressed.



Abstract In order to search for new bioactive substances from marine organisms, we have investigated the acetone extracts of the soft coral Sarcophyton ehrenbergi collected at San-Hsian-Tai, Taitong County, Taiwan. Chromatographic fractionation of the extracts of the octocoral S. ehrenbergi led to the isolation of three new cembranoids, +-12-ethoxycarbonyl-11Z-sarcophine 1, ehrenbergol A and B 2 and 3. The structures of these isolated metabolites were elucidated through extensive spectroscopic analyses. Moreover, metabolites 1–3 were evaluated in vitro for their cytotoxicity towards selected cancer cell lines and antiviral activity against human cytomegalovirus HCMV. View Full-Text

Keywords: Sarcophyton ehrenbergi; cembranoids; cytotoxicity; anti-HCMV Sarcophyton ehrenbergi; cembranoids; cytotoxicity; anti-HCMV





Author: Shang-Kwei Wang 1,2, Mu-Keng Hsieh 3 and Chang-Yih Duh 1,3,*

Source: http://mdpi.com/



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