Marine Peptides as Potential Agents for the Management of Type 2 Diabetes Mellitus—A ProspectReport as inadecuate


Marine Peptides as Potential Agents for the Management of Type 2 Diabetes Mellitus—A Prospect


Marine Peptides as Potential Agents for the Management of Type 2 Diabetes Mellitus—A Prospect - Download this document for free, or read online. Document in PDF available to download.

Dongguan Key Laboratory of Environmental Medicine, School of Public Health, Guangdong Medical University, Dongguan 523808, China





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Academic Editor: Se-Kwon Kim

Abstract An increasing prevalence of diabetes is known as a main risk for human health in the last future worldwide. There is limited evidence on the potential management of type 2 diabetes mellitus using bioactive peptides from marine organisms, besides from milk and beans. We summarized here recent advances in our understanding of the regulation of glucose metabolism using bioactive peptides from natural proteins, including regulation of insulin-regulated glucose metabolism, such as protection and reparation of pancreatic β-cells, enhancing glucose-stimulated insulin secretion and influencing the sensitivity of insulin and the signaling pathways, and inhibition of bioactive peptides to dipeptidyl peptidase IV, α-amylase and α-glucosidase activities. The present paper tried to understand the underlying mechanism involved and the structure characteristics of bioactive peptides responsible for its antidiabetic activities to prospect the utilization of rich marine organism proteins. View Full-Text

Keywords: marine protein; bioactive peptide; regulation; glucose metabolism; structure active relationship marine protein; bioactive peptide; regulation; glucose metabolism; structure active relationship





Author: En-Qin Xia, Shan-Shan Zhu, Min-Jing He, Fei Luo, Cheng-Zhan Fu and Tang-Bin Zou *

Source: http://mdpi.com/



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