The Impacts of Obesity and Metabolic Abnormality on Carotid Intima-Media Thickness and Non-Alcoholic Fatty Liver Disease in Children from an Inland Chinese CityReport as inadecuate




The Impacts of Obesity and Metabolic Abnormality on Carotid Intima-Media Thickness and Non-Alcoholic Fatty Liver Disease in Children from an Inland Chinese City - Download this document for free, or read online. Document in PDF available to download.

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Departments of Endocrinology, the First Peoples Hospital, 39 Dongmaoling Road, Yueyang 414000, Hunan, China

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Palmer Laboratory of Cell & Molecular Biology, PCCR, Palmer College of Chiropractic-Florida, 4705 S. Clyde Morris Blvd, Port Orange, FL 32129, USA

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Departments of Ultrasound, the First Peoples Hospital, 39 Dongmaoling Road, Yueyang 414000, Hunan, China





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Author to whom correspondence should be addressed.



Abstract The Chinese inland, where low child obesity and overweight rates were reported in earlier studies, has recently experienced rapid economy changes. This may impact children’s health. In the present study, we investigated the obesity rate, metabolic health status, and their impacts on carotid intima-media thickness IMT and non-alcoholic fatty liver disease NAFLD among children from Yueyang, an inland city of China. We found that the obesity rate was about 5% for both 7- and 11-year olds. Overweightness rates were 9.5% and 11.5% for the 7- and 11-year olds, respectively. Clinical and laboratory examinations revealed significant differences among different weight groups in the 11-year old volunteers, which were absent in the 7-year olds. Further statistical analysis showed that: age, BMI, blood pressure, triglyceride level, and metabolic abnormality were positively correlated to carotid IMT; triglyceride level, obesity, male, and the number of metabolic abnormalities were independent risk factors for NAFLD in these children. Our study suggests that: childhood overweightness and obesity are now epidemic in Yueyang, which have contributed to increased carotid IMT and may also increased NAFLD incidents; and serum triglyceride level is a critical factor in the development of childhood NAFLD. Thus, childhood metabolic health warrants further vigorous research in the inland of China. View Full-Text

Keywords: Yueyang; metabolic syndrome; carotid intima-media thickness; public health; non-alcoholic fatty liver disease Yueyang; metabolic syndrome; carotid intima-media thickness; public health; non-alcoholic fatty liver disease





Author: Xiao-Yue Wang 1, Xiang-Hua Zhang 1, Chao Hua Yao 2, Hong-Hui Zhu 3 and Liang Zhang 2,*

Source: http://mdpi.com/



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