Pregnancy Loss Following Amniocentesis or CVS Sampling—Time for a Reassessment of RiskReport as inadecuate




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1

Guys and St. Thomas NHS Foundation Trust and Kings College, London SE1 9RT, UK

2

Medway Maritime Hospital, Gillingham, Kent ME7 5NY, UK

3

Kings College Hospital, Denmark Hill, London SE5 9RS, UK





*

Author to whom correspondence should be addressed.



Abstract Risk of procedure-related pregnancy loss is currently widely quoted in the UK as 1% for amniocentesis and 1.5% for chorionic villus sampling. Published data suggest that these risk figures are out of date and inaccurate, and that new guidelines are required for pre-test counseling. It is our opinion that accurate and evidence-based information concerning miscarriage risk is vital when counseling women, as exaggeration of this risk may deter women from testing, or cause unjustified remorse if a miscarriage ensues. It is also essential that health-care economists are aware of the up-to-date evidence on -procedure-related risk- when applying risk-benefit analysis to assess new technology for non-invasive screening. View Full-Text

Keywords: miscarriage; procedure-related pregnancy loss; amniocentesis; chorionic villus sampling CVS; non-invasive prenatal testing; cell free fetal DNA miscarriage; procedure-related pregnancy loss; amniocentesis; chorionic villus sampling CVS; non-invasive prenatal testing; cell free fetal DNA





Author: Caroline Ogilvie 1,* and Ranjit Akolekar 2,3

Source: http://mdpi.com/



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