Inflammatory and Other Biomarkers: Role in Pathophysiology and Prediction of Gestational Diabetes MellitusReport as inadecuate




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1

Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Clayton 3168, Australia

2

Diabetes and Vascular Medicine Unit, Monash Health, Clayton 3168, Australia

3

Monash Womens Services, Monash Health, Clayton 3168, Australia





*

Author to whom correspondence should be addressed.



Academic Editor: Philip Newton Baker

Abstract Understanding pathophysiology and identifying mothers at risk of major pregnancy complications is vital to effective prevention and optimal management. However, in current antenatal care, understanding of pathophysiology of complications is limited. In gestational diabetes mellitus GDM, risk prediction is mostly based on maternal history and clinical risk factors and may not optimally identify high risk pregnancies. Hence, universal screening is widely recommended. Here, we will explore the literature on GDM and biomarkers including inflammatory markers, adipokines, endothelial function and lipids to advance understanding of pathophysiology and explore risk prediction, with a goal to guide prevention and treatment of GDM. View Full-Text

Keywords: biomarkers; inflammatory markers; pregnancy; gestational diabetes mellitus; risk prediction biomarkers; inflammatory markers; pregnancy; gestational diabetes mellitus; risk prediction





Author: Sally K. Abell 1,2, Barbora De Courten 1,2, Jacqueline A. Boyle 1,2,3 and Helena J. Teede 1,2,*

Source: http://mdpi.com/



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