Role of Teriparatide in Medication-Related Osteonecrosis of the Jaws MRONJReport as inadecuate




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1

Center for Refractory Jawbone Diseases, Department of Oral and Maxillofacial Surgery, Kyung Hee University Dental Hospital, Seoul 02447, Korea

2

Department of Nuclear Medicine, Kyung Hee University Hospital, Seoul 02447, Korea





*

Author to whom correspondence should be addressed.



Academic Editor: Christian Walter

Abstract While the optimal treatment concept of medication-related osteonecrosis of the jaws MRONJ is still in debate, several adjunct therapies have been introduced. Among these adjunctive measures, recombinant human parathyroid hormone rhPTH, teriparatide seems to be the most promising treatment modality. Several studies have presented the beneficial effect of short-term teriparatide; they have shown an improved level of bone markers and radiographic evidence of bone healing. Although clinical validation by a controlled trial with prospective design would be essential, short-term teripratide therapy would be a good treatment option for MRONJ patients with impaired bone remodeling. View Full-Text

Keywords: MRONJ; bisphosphonate; ONJ; teriparatide; parathyroid hormone MRONJ; bisphosphonate; ONJ; teriparatide; parathyroid hormone





Author: Yong-Dae Kwon 1,* and Deog-Yoon Kim 2

Source: http://mdpi.com/



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