Comparison of Electrochemical Immunosensors and Aptasensors for Detection of Small Organic Molecules in Environment, Food Safety, Clinical and Public SecurityReport as inadecuate




Comparison of Electrochemical Immunosensors and Aptasensors for Detection of Small Organic Molecules in Environment, Food Safety, Clinical and Public Security - Download this document for free, or read online. Document in PDF available to download.

University Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086 CNRS, 15 rue J-A de Baïf, Paris 75205, France



These authors contributed equally to this work.





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Academic Editors: Nicole Jaffrezic-Renault and Carole Chaix

Abstract We review here the most frequently reported targets among the electrochemical immunosensors and aptasensors: antibiotics, bisphenol A, cocaine, ochratoxin A and estradiol. In each case, the immobilization procedures are described as well as the transduction schemes and the limits of detection. It is shown that limits of detections are generally two to three orders of magnitude lower for immunosensors than for aptasensors, due to the highest affinities of antibodies. No significant progresses have been made to improve these affinities, but transduction schemes were improved instead, which lead to a regular improvement of the limit of detections corresponding to ca. five orders of magnitude over these last 10 years. These progresses depend on the target, however. View Full-Text

Keywords: immunosensor; aptasensor; ciprofloxacin; enrofloxacin; ofloxacin; tetracyclines; neomycin; tobramycin; ampicillin; kanamycin; sulfonamides; bisphenol A; cocaine; ochratoxin A; estradiol immunosensor; aptasensor; ciprofloxacin; enrofloxacin; ofloxacin; tetracyclines; neomycin; tobramycin; ampicillin; kanamycin; sulfonamides; bisphenol A; cocaine; ochratoxin A; estradiol





Author: Benoit Piro †,* , Shihui Shi †, Steeve Reisberg †, Vincent Noël † and Guillaume Anquetin †

Source: http://mdpi.com/



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