Blueberries’ Impact on Insulin Resistance and Glucose IntoleranceReport as inadecuate


Blueberries’ Impact on Insulin Resistance and Glucose Intolerance


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Department of Human Ecology, University of Maryland Eastern Shore, Princess Anne, MD 21853, USA





Academic Editor: Dorothy Klimis-Zacas

Abstract Blueberries are a rich source of polyphenols, which include anthocyanin bioactive compounds. Epidemiological evidence indicates that incorporating blueberries into the diet may lower the risk of developing type 2 diabetes T2DM. These findings are supported by pre-clinical and clinical studies that have shown improvements in insulin resistance i.e., increased insulin sensitivity after obese and insulin-resistant rodents or humans consumed blueberries. Insulin resistance was assessed by homeostatic model assessment-estimated insulin resistance HOMA-IR, insulin tolerance tests, and hyperinsulinemic-euglycemic clamps. Additionally, the improvements in glucose tolerance after blueberry consumption were assessed by glucose tolerance tests. However, firm conclusions regarding the anti-diabetic effect of blueberries cannot be drawn due to the small number of existing clinical studies. Although the current evidence is promising, more long-term, randomized, and placebo-controlled trials are needed to establish the role of blueberries in preventing or delaying T2DM. View Full-Text

Keywords: blueberries; bilberries; strawberries; cranberries; berries; anthocyanins; diabetes; insulin; glucose; diabetes blueberries; bilberries; strawberries; cranberries; berries; anthocyanins; diabetes; insulin; glucose; diabetes





Author: April J. Stull

Source: http://mdpi.com/



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