Vol 7: Vitamin B12 Supplementation in Treating Major Depressive Disorder: A Randomized Controlled Trial.Report as inadecuate



 Vol 7: Vitamin B12 Supplementation in Treating Major Depressive Disorder: A Randomized Controlled Trial.


Vol 7: Vitamin B12 Supplementation in Treating Major Depressive Disorder: A Randomized Controlled Trial. - Download this document for free, or read online. Document in PDF available to download.

Download or read this book online for free in PDF: Vol 7: Vitamin B12 Supplementation in Treating Major Depressive Disorder: A Randomized Controlled Trial.
This article is from The Open Neurology Journal, volume 7.AbstractBackground-Objective: : Recent literature has identified links between vitamin B12 deficiency and depression.We compared the clinical response of SSRI-monotherapy with that of B12-augmentation in a sample of depressed patients with low normal B12 levels who responded inadequately to the first trial with the SSRIs. Methods: : Patients with depression and low normal B12 levels were randomized to a control arm antidepressant only or treatment arm antidepressants and injectable vitamin B12 supplementation. Results: : A total of 199 depressed patients were screened. Out of 73 patients with low normal B12 levels 34 47% were randomized to the treatment group while 39 53% were randomized to the control arm. At three months follow up 100% of the treatment group showed at least a 20% reduction in HAM-D score, while only 69% in the control arm showed at least a 20% reduction in HAM-D score p



Author: Syed, Ehsan Ullah; Wasay, Mohammad; Awan, Safia

Source: https://archive.org/







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