Vol 41: Vitamin D deficiency in women with polycystic ovary syndrome.Report as inadecuate



 Vol 41: Vitamin D deficiency in women with polycystic ovary syndrome.


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This article is from Clinical and Experimental Reproductive Medicine, volume 41.AbstractObjective: To investigate: the prevalence of vitamin D deficiency in Korean women with polycystic ovary syndrome PCOS, and the relationship between vitamin D status and clinical or metabolic features in this group. Methods: We recruited 38 women with PCOS using the Rotterdam criteria. A total of 109 premenopausal control women were matched with patients based on age and body mass index. Serum 25-hydroxy vitamin D concentrations less than 20 ng-mL were classified as frank vitamin D deficiency. Since vitamin D may play a significant role in metabolic disturbances in women with PCOS, correlations between clinical or metabolic parameters and vitamin D status were analyzed separately in patients and controls. Results: Women with PCOS showed no differences in the level of 25-hydroxy vitamin D 19.6±6.6 ng-mL in patients vs. 20.1±7.4 ng-mL in controls, respectively, p=0.696 or prevalence of vitamin D deficiency 57.9% in patients vs. 56.5% in controls, respectively, p=0.880. In addition, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles in either PCOS patients or controls. Conclusion: Our study found no differences in the absolute level of serum vitamin D between PCOS patients and matched controls. Prevalence of vitamin D deficiency was equally common among both patients and controls. Additionally, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles, suggesting that the role of vitamin D in the pathogenesis of PCOS is not yet clear.



Author: Kim, Jin Ju; Choi, Young Min; Chae, Soo Jin; Hwang, Kyu Ri; Yoon, Sang Ho; Kim, Min Jeong; Kim, Sun Mie; Ku, Seung Yup; Kim, Seok Hyun; Kim, Jung Gu

Source: https://archive.org/







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