Vol 9: Tumor-Associated Neutrophils as a New Prognostic Factor in Cancer: A Systematic Review and Meta-Analysis.Report as inadecuate



 Vol 9: Tumor-Associated Neutrophils as a New Prognostic Factor in Cancer: A Systematic Review and Meta-Analysis.


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This article is from PLoS ONE, volume 9.AbstractPurpose: Tumor-associated neutrophils TAN have been reported in a variety of malignancies. We conducted an up-to-date meta-analysis to evaluate the prognostic role of TAN in cancer. Method: Pubmed, Embase and web of science databases were searched for studies published up to April 2013. Pooled hazard ratios HRs and their corresponding 95% confidence intervals CIs were calculated. The impact of neutrophils localization and primary antibody were also assessed. Results: A total of 3946 patients with various solid tumors from 20 studies were included. High density of intratumoral neutrophils were independently associated with unfavorable survival; the pooled HRs were 1.68 95%CI: 1.36–2.07, I2 = 55.8%, p



Author: Shen, Meixiao; Hu, Pingping; Donskov, Frede; Wang, Guanghui; Liu, Qi; Du, Jiajun

Source: https://archive.org/







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