Vol 3: Screening of Different Organs of Rats for HCA2 Receptor mRNA.Report as inadecuate



 Vol 3: Screening of Different Organs of Rats for HCA2 Receptor mRNA.


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This article is from International Journal of Molecular and Cellular Medicine, volume 3.AbstractInterest in hydroxy - carboxylic acid 2 HCA2 receptor has been raised since it is the target of antidyslipidemic drug nicotinic acid. The present study aimed to evaluate the presence of mRNA of this receptor in different organs of laboratory rat. Twenty two different organs of rats including mesenteric fat, epididymis head, body and tail, testis, ovary, xiphoid process, liver, adrenal gland, femoral head, proximal epiphyseal and metaphyseal bone marrow of femur, esophagus, glandular stomach, forestomach, intestines, colons, heart, spleen, kidney, trachea, lung, skeletal muscle quadriceps, cerebrum and cerebellum were removed and examined for HCA2 mRNA by RT- PCR method. The mRNA for HCA2 receptor was detected in all analyzed tissues. In conclusion, the different organs of rat express HCA2 receptor mRNA which makes a proper animal model for future studies on the physiological and pharmacological roles of this receptor in vivo.



Author: Shomali, Tahoora; Mosleh, Najmeh; Kamalpour, Mohammad

Source: https://archive.org/







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