Vol 3: Successive exposure to moderate hypoxia does not affect glucose metabolism and substrate oxidation in young healthy men.Report as inadecuate



 Vol 3: Successive exposure to moderate hypoxia does not affect glucose metabolism and substrate oxidation in young healthy men.


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This article is from SpringerPlus, volume 3.AbstractIntroduction: Exposure to hypoxia has been suggested to acutely alter glucose regulation. However, the effects of successive exposure to moderate hypoxia on postprandial glucose regulation and substrate oxidation pattern after multiple meals have not been elucidated. Purpose: We examined the effects of successive exposure to moderate hypoxia on metabolic responses and substrate oxidation pattern. Methods: Eight healthy men 21.0 ± 0.6 yrs, 173 ± 2.3 cm, 70.6 ± 5.0 kg, 23.4 ± 1.1 kg-m2 completed two experimental trials on separate days: a rest trial under normoxic conditions FiO2 = 20.9% and a rest trial under hypoxic conditions FiO2 = 15.0%. Experimental trials were performed over 7 h in an environmental chamber. Blood and respiratory gas samples were collected over 7 h. Standard meals were provided 1 h 745 kcal and 4 h 731 kcal after entering the chamber. Results: Although each meal significantly increased blood glucose and serum insulin concentrations P 



Author: Morishima, Takuma; Goto, Kazushige

Source: https://archive.org/







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