Vol 55: Preoperative Weakness and Demyelination of the Corticospinal Tract in Meningioma Patients : Changes in Diffusion Parameters Using Diffusion Tensor Imaging.Report as inadecuate



 Vol 55: Preoperative Weakness and Demyelination of the Corticospinal Tract in Meningioma Patients : Changes in Diffusion Parameters Using Diffusion Tensor Imaging.


Vol 55: Preoperative Weakness and Demyelination of the Corticospinal Tract in Meningioma Patients : Changes in Diffusion Parameters Using Diffusion Tensor Imaging. - Download this document for free, or read online. Document in PDF available to download.

Download or read this book online for free in PDF: Vol 55: Preoperative Weakness and Demyelination of the Corticospinal Tract in Meningioma Patients : Changes in Diffusion Parameters Using Diffusion Tensor Imaging.
This article is from Journal of Korean Neurosurgical Society, volume 55.AbstractObjective: Differentiation of demyelination in white matter from axonal damage can be determined using diffusion tensor imaging DTI. In this study using meningioma patients an attempt was made to evaluate the relationship between preoperative weakness and the changes of diffusion parameters in the corticospinal tract CST using DTI. Methods: Twenty-six patients with meningioma were enrolled in this study. Eleven of them suffered from objective motor weakness and were classified as Group 1. The remaining 15 patients did not present motor weakness and were classified as Group 2. Fiber tractography and CST diffusion parameters were obtained using DTIStudio. The ratios lesion side mean value-contralateral side mean value of CST diffusion parameters were compared with 1.0 as a test value using a one-sample t-test. Results: In Group 1, fractional anisotropy FA, tensor trace TT, and radial diffusivity RD, λ2 and λ3 of the CST were significantly different between two hemispheres, but axial diffusivity AD, λ1 of the CST was not significantly different between two hemispheres. In Group 2, FA and λ3 of CST did not differ significantly between the hemispheres. In Group 2, TT, λ1, and λ2 of CST in the ipsilateral hemisphere were significantly higher than those of the unaffected hemisphere. However, the differences were small. Conclusion: Motor weakness was related to a low FA and high TT resulting from increased RD of the CST fibers. CST diffusion changes in patients with weakness are similar to those for demyelination.



Author: Kim, Myoung Soo; Chung, Chun Kee; Jung, Hee-Won; Park, Chul-Kee; Kim, Chi Heon; Kim, June Sic

Source: https://archive.org/







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