Vol 68: Palmitic acid in the sn-2 position of dietary triacylglycerols does not affect insulin secretion or glucose homeostasis in healthy men and women.Report as inadecuate



 Vol 68: Palmitic acid in the sn-2 position of dietary triacylglycerols does not affect insulin secretion or glucose homeostasis in healthy men and women.


Vol 68: Palmitic acid in the sn-2 position of dietary triacylglycerols does not affect insulin secretion or glucose homeostasis in healthy men and women. - Download this document for free, or read online. Document in PDF available to download.

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This article is from European Journal of Clinical Nutrition, volume 68.AbstractBackground-objectives:: Dietary triacylglycerols containing palmitic acid in the sn-2 position might impair insulin release and increase plasma glucose. Subjects-Methods:: We used a cross-over designed feeding trial in 53 healthy Asian men and women 20–50 years to test this hypothesis by exchanging 20% energy of palm olein PO; control with randomly interesterified PO IPO or high oleic acid sunflower oil HOS. After a 2-week run-in period on PO, participants were fed PO, IPO and HOS for 6 week consecutively in randomly allocated sequences. Fasting midpoint and endpoint and postprandial blood at the endpoint following a test meal 3.54 MJ, 14 g protein, 85 g carbohydrate and 50 g fat as PO were collected for the measurement of C-peptide, insulin, glucose, plasma glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1, lipids and apolipoproteins; pre-specified primary and secondary outcomes were postprandial changes in C-peptide and plasma glucose. Results:: Low density lipoprotein cholesterol was 0.3 mmol-l 95% confidence interval 95% CI 0.1, 0.5; P



Author: Filippou, A; Teng, K-T; Berry, S E; Sanders, T A B

Source: https://archive.org/







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