Vol 8: Mycetoma: Experience of 482 Cases in a Single Center in Mexico.Report as inadecuate



 Vol 8: Mycetoma: Experience of 482 Cases in a Single Center in Mexico.


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This article is from PLoS Neglected Tropical Diseases, volume 8.AbstractMycetoma is a chronic granulomatous disease. It is classified into eumycetoma caused by fungi and actinomycetoma due to filamentous actinomycetes. Mycetoma can be found in geographic areas in close proximity to the Tropic of Cancer. Mexico is one of the countries in which this disease is highly endemic. In this retrospective study we report epidemiologic, clinical and microbiologic data of mycetoma observed in the General Hospital of Mexico in a 33 year-period 1980 to 2013. A total of 482 cases were included which were clinical and microbiology confirmed. Four hundred and forty four cases 92.11% were actinomycetomas and 38 cases 7.88% were eumycetomas. Most patients were agricultural workers; there was a male predominance with a sex ratio of 3∶1. The mean age was 34.5 years old most ranged from 21 to 40 years. The main affected localization was lower and upper limbs 70.74% and 14.52% respectively. Most of the patients came from humid tropical areas Morelos, Guerrero and Hidalgo were the regions commonly reported. The main clinical presentation was as tumor-like soft tissue swelling with draining sinuses 97.1%. Grains were observed in all the cases. The principal causative agents for actinomycetoma were: Nocardia brasiliensis 78.21% and Actinomadura madurae 8.7%; meanwhile, for eumycetomas: Madurella mycetomatis and Scedosporium boydii synonym: Pseudallescheria boydii were identified. This is a single-center, with long-follow up, cross-sectional study that allows determining the prevalence and characteristics of mycetoma in different regions of Mexico.



Author: Bonifaz, Alexandro; Tirado-Sanchez, Andres; Calderon, Luz; Saul, Amado; Araiza, Javier; Hernandez, Marco; Gonzalez, Gloria M.; Ponce, Rosa Maria

Source: https://archive.org/







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