A cinética do chumbo no organismo humano e sua importância para a saúde Report as inadecuate




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Josino Costa Moreira ;Ciência & Saúde Coletiva 2004, 9 1

Author: Fátima Ramos Moreira

Source: http://www.redalyc.org/


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Ciência & Saúde Coletiva ISSN: 1413-8123 cecilia@claves.fiocruz.br Associação Brasileira de Pós-Graduação em Saúde Coletiva Brasil Ramos Moreira, Fátima; Costa Moreira, Josino A cinética do chumbo no organismo humano e sua importância para a saúde Ciência & Saúde Coletiva, vol.
9, núm.
1, 2004, pp.
167-181 Associação Brasileira de Pós-Graduação em Saúde Coletiva Rio de Janeiro, Brasil Disponível em: http:--www.redalyc.org-articulo.oa?id=63013499017 Como citar este artigo Número completo Mais artigos Home da revista no Redalyc Sistema de Informação Científica Rede de Revistas Científicas da América Latina, Caribe , Espanha e Portugal Projeto acadêmico sem fins lucrativos desenvolvido no âmbito da iniciativa Acesso Aberto 16 Lead kinetics in human body and its significance to health Fátima Ramos Moreira 1 Josino Costa Moreira 1 Abstract Lead is one of the most common pollutants in the environment.
It is considered toxic to the human beings and animals and without any physiological known function in the organism. Lead toxic effects can affect almost all organs and systems of the body.
Lead enters the body primarily through inhalation or ingestion, being directly absorbed, distributed, and excreted.
The primary sites for inorganic lead absorption are gastrointestinal and respiratory tract.
Once absorbed, lead is found in blood, soft tissues and mineralizing systems.
Approximately 90% of the total body burden of lead is found in bones, body’s major storage site.
Around 5% of lead in blood is in plasma, representing the labile and biologically active lead fraction, able to pass the cells membranes and cause toxic effects.
The absorbed lead is excreted mainly through urine and feces.
Thus the knowledge of the lead kinetics is important to a greater understanding on lead toxicity, since the risks of health adverse effects are related to the total body burden of lead. Key words Lead, Kinetics, Bone, Plasma 1 Centro de Estudos da Saú...





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