Epstein–Barr virus-associated inflammatory pseudotumor of the spleen: report of two cases and review of the literatureReport as inadecuate




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Journal of Hematopathology

, Volume 2, Issue 2, pp 127–131

First Online: 31 March 2009Received: 04 October 2008Accepted: 04 March 2009

Abstract

We report two rare examples of Epstein–Barr virus EBV-associated inflammatory pseudotumor of the spleen. One patient presented with night sweats, abdominal pain, and weight loss and was found to have a splenic mass on CT scan suspected of lymphoma. The splenic mass in second patient was found incidentally at the time of work up for kidney stones. The pathologic examination of these splenectomy specimens showed similar histologic features. However, the spindle cells were composed of EBV-infected follicular dendritic cells in one case whereas the second case lacked significant follicular dendritic cell proliferation and showed only focal EBV-infected cells suggesting that these proliferations are heterogenous in nature.

KeywordsSplenic inflammatory pseudotumor Epstein–Barr virus Follicular dendritic cell  Download fulltext PDF



Author: Lizabeth Rosenbaum - M. Houman Fekrazad - Ian Rabinowitz - Mohammad A. Vasef

Source: https://link.springer.com/







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