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Experimental Brain Research

, Volume 196, Issue 3, pp 467–474

First Online: 31 May 2009Received: 23 January 2009Accepted: 14 May 2009

Abstract

The inhibitory control of actions has been claimed to rely on dopaminergic pathways. Given that this hypothesis is mainly based on patient and drug studies, some authors have questioned its validity and suggested that beneficial effects of dopaminergic stimulants on response inhibition may be limited to cases of suboptimal inhibitory functioning. We present evidence that, in carefully selected healthy adults, spontaneous eyeblink rate, a marker of central dopaminergic functioning, reliably predicts the efficiency in inhibiting unwanted action tendencies in a stop-signal task. These findings support the assumption of a modulatory role for dopamine in inhibitory action control.

KeywordsResponse inhibition Dopamine Spontaneous eyeblink  Download fulltext PDF



Author: Lorenza Serena Colzato - Wery P. M. van den Wildenberg - Nelleke C. van Wouwe - Merel M. Pannebakker - Bernhard Hommel

Source: https://link.springer.com/







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