DetectiV: visualization, normalization and significance testing for pathogen-detection microarray dataReport as inadecuate




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Genome Biology

, 8:R190

First Online: 14 September 2007Received: 01 June 2007Revised: 15 August 2007Accepted: 14 September 2007

Abstract

DNA microarrays offer the possibility of testing for the presence of thousands of micro-organisms in a single experiment. However, there is a lack of reliable bioinformatics tools for the analysis of such data. We have developed DetectiV, a package for the statistical software R. DetectiV offers powerful yet simple visualization, normalization and significance testing tools. We show that DetectiV performs better than previously published software on a large, publicly available dataset.

AbbreviationsDFAdirect fluorescent antibody

FMDVfoot-and-mouth disease virus

GEOGene Expression Omnibus

IBVinfectious bronchitis virus.

Electronic supplementary materialThe online version of this article doi:10.1186-gb-2007-8-9-r190 contains supplementary material, which is available to authorized users.

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Author: Michael Watson - Juliet Dukes - Abu-Bakr Abu-Median - Donald P King - Paul Britton

Source: https://link.springer.com/







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