Stability of real-time MR temperature mapping in healthy and diseased human liverReport as inadecuate

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1 LaBRI - Laboratoire Bordelais de Recherche en Informatique 2 IHU-LIRYC 3 IMB - Institut de Mathématiques de Bordeaux 4 Hôpital Saint-André 5 UMC Utrecht

Abstract : Purpose: To determine the stability and quality of MR temperature mapping using the proton resonance frequency PRF method in the liver of hepatic tumor patients.Material and Methods: The standard deviation of a series of temperature maps was determined in 30 patients 21 cirrhotic livers with carcinoma, 9 non-cirrhotic livers with metastasis or angioma and in 5 volunteers at normal body temperature under free breathing. A respiratory-gated segmented EPI sequence 3 slices in 1 expiration phase was performed with SENSE acceleration on a 1.5 T scanner. Motion corrupted images were identified by calculation of the cross-correlation coefficient and discarded.Results: A T 2* range of 10-33 ms was found with especially low values in advanced cirrhotic livers. The mean temperature standard deviation in patients was 2.3°C range 1.5-5.0°C. The stability in healthy livers was slightly better than that in cirrhotic livers, and it was higher in the right than in the left liver. The gaiting failed in 4 % of the images when the respiratory cycle was irregular, leading to motion artifacts and errors in the temperature maps.Conclusion: The achieved temperature stability and image quality makes real-time quantitative monitoring of thermal ablation of liver tumors feasible on a clinical scanner.

Author: Claudia Weidensteiner - Noureddine Kerioui Bruno Quesson - Baudouin Denis de Senneville - Hervé Trillaud - Chrit Moonen -



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