Synthesis and general properties of silated-hydroxypropyl methylcellulose in prospect of biomedical use.Report as inadecuate




Synthesis and general properties of silated-hydroxypropyl methylcellulose in prospect of biomedical use. - Download this document for free, or read online. Document in PDF available to download.

* Corresponding author 1 LIOAD - Laboratoire d-ingénierie osteo-articulaire et dentaire 2 DMCTT - Département Matériaux

Abstract : Synthesis of grafting silane on a hydro soluble cellulose ether HPMC was described. In alkaline medium, this derivate is under gel form. With a decrease of the pH, a self-hardening occurs due to the silanol condensation. For potential biomedical use, we described the silated-HPMC synthesis, the gel behavior after steam sterilization and the parameters of the silanol condensation i.e. pH, silane percentage and temperature. Minimum kinetic of the condensation was observed for pH between 5.5 and 6.5. So temperature catalyzed the reaction and the self-hardening speed was increased by silane percentage.





Author: Xavier Bourges - Pierre Weiss - Guy Daculsi - Gilbert Legeay -

Source: https://hal.archives-ouvertes.fr/



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