A Case of Corticobasal Degeneration Studied with Positron Emission TomographyReport as inadecuate




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Behavioural Neurology - Volume 6 1993, Issue 1, Pages 59-64

Case Report

Department of Neurology, Institute of Brain Diseases, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980, Japan

Cyclotron and Radioisotope Center, Tohoku University, Aramaki Aoba, Aoba-ku, Sendai 980, Japan

Received 25 January 1993; Accepted 10 February 1993

Copyright © 1993 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We measured cerebral blood flow, oxygen metabolism, glucose utilization, and dopamine metabolism in the brain of a patient with corticobasal degeneration using positron emission tomography PET. The clinical picture is distinctive, comprising features referable to both cortical and basal ganglionic dysfunction. Brain imagings of glucose and dopamine metabolism can demonstrate greater abnormalities in the cerebral cortex and in the striatum contralateral to the more affected side than those of blood flow and oxygen metabolism. This unique combination study measuring both cerebral glucose utilization and dopamine metabolism in the nigrostriatal system can provide efficient information about the dysfunctions which are correlated with individual clinical symptoms, and this study is essential to diagnosis of corticobasal degeneration.





Author: H. Nagasawa, T. Imamura, H. Nomura, M. Itoh, and T. Ido

Source: https://www.hindawi.com/



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