The Effect of Age on Fracture Risk: A Population-Based Cohort StudyReport as inadecuate

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Journal of Aging Research - Volume 2016 2016, Article ID 5071438, 5 pages -

Research ArticleNational Drug Research Institute, Curtin University, GPO Box U1987, Perth, WA 6845, Australia

Received 15 April 2016; Accepted 12 May 2016

Academic Editor: F. R. Ferraro

Copyright © 2016 Wenbin Liang and Tanya Chikritzhs. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aim. To precisely estimate the effect of age on the risk of fracture hospitalisation among the Western Australia population over the life course. Methods. This population-based cohort study used hospital data on fractures for the period January 1991 to January 2013 among Western Australians born between 1915 and 1990. Results. The average incidence rates per 10,000 person-years of fracture hospitalisation 95% confidence interval were 50.12 49.90, 50.35, 55.14 54.82, 55.48, and 45.02 44.71, 45.32 for both males and females, males only, and females only, respectively. The age-specific rate of fracture hospitalisation in natural logarithm form in adults >18 years was well predicted by age at its 1st, 2nd, and 3rd power in males with an adjusted -squared of 0.98 and . For females, the trend was also well predicted by its 1st and 2nd powers the 3rd power term of age was removed due to its value > 0.8 with an adjusted -squared of 0.99 and . Conclusions. Overall trends in age and gender specific risk of fracture among the Western Australian population were similar to estimates reported from previous studies. The trend in fracture hospitalisation risk over the life course can be almost fully explained by age.

Author: Wenbin Liang and Tanya Chikritzhs



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