Decreases in blood perfusion of the anterior cingulate gyri in Anorexia Nervosa Restricters assessed by SPECT image analysisReport as inadecuate




Decreases in blood perfusion of the anterior cingulate gyri in Anorexia Nervosa Restricters assessed by SPECT image analysis - Download this document for free, or read online. Document in PDF available to download.

BMC Psychiatry

, 1:2

First Online: 04 June 2001Received: 19 February 2001Accepted: 04 June 2001

Abstract

BackgroundIt is possible that psychopathological differences exist between the restricting and bulimic forms of anorexia nervosa. We investigated localized differences of brain blood flow of anorexia nervosa patients using SPECT image analysis with statistic parametric mapping SPM in an attempt to link brain blood flow patterns to neurophysiologic characteristics.

MethodsThe subjects enrolled in this study included the following three groups: pure restrictor anorexics AN-R, anorexic bulimics AN-BP, and healthy volunteers HV. All images were transformed into the standard anatomical space of the stereotactic brain atlas, then smoothed. After statistical analysis of each brain image, the relationships among images were evaluated.

ResultsSPM analysis of the SPECT images revealed that the blood flow of frontal area mainly containing bilateral anterior cingulate gyri ACC was significantly decreased in the AN-R group compared to the AN-BP and HV groups.

ConclusionsThese findings suggest that some localized functions ofthe ACCare possibly relevant to the psychopathological aspects of AN-R.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-244X-1-2 contains supplementary material, which is available to authorized users.

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Author: Tetsuro Naruo - Yoshiaki Nakabeppu - Daisuke Deguchi - Nobuatsu Nagai - Junko Tsutsui - Masayuki Nakajo - Shin-ichi Nozoe

Source: https://link.springer.com/



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