Surface-based electrophysiology modeling and assessment of physiological simulations in atriaReport as inadecuate




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* Corresponding author 1 M3DISIM - Mathematical and Mechanical Modeling with Data Interaction in Simulations for Medicine LMS - Laboratoire de mécanique des solides, Inria Saclay - Ile de France 2 REO - Numerical simulation of biological flows LJLL - Laboratoire Jacques-Louis Lions, Inria Paris-Rocquencourt, UPMC - Université Pierre et Marie Curie - Paris 6 3 Hôpital Haut-Lévêque

Abstract : The objective of this paper is to assess a previously-proposed surface-based electrophysiology model with detailed atrial simulations. This model - derived and substantiated by mathematical arguments - is specifically designed to address thin structures such as atria, and to take into account strong anisotropy effects related to fiber directions with possibly rapid variations across the wall thickness. The simulation results are in excellent adequacy with previous studies, and confirm the importance of anisotropy effects and variations thereof. Furthermore, this surface-based model provides dramatic computational benefits over 3D models with preserved accuracy.

Keywords : Electrophysiology modelling Asymptotic analysis Cardiology





Author: Annabelle Collin - Jean-Frédéric Gerbeau - Mélèze Hocini - Michel Haïssaguerre - Dominique Chapelle -

Source: https://hal.archives-ouvertes.fr/



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