Update on Repetitive Transcranial Magnetic Stimulation in Obsessive-Compulsive Disorder: Different TargetsReport as inadecuate




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Current Psychiatry Reports

, Volume 13, Issue 4, pp 289–294

First Online: 06 May 2011

Abstract

Obsessive-compulsive disorder OCD is a chronic, disabling disorder. Ten percent of patients remain treatment refractory despite several treatments. For these severe, treatment-refractory patients, repetitive transcranial magnetic stimulation rTMS has been suggested as a treatment option. Since 1997, in published trials, a total of 110 OCD patients have been treated with rTMS. This review aims to provide an update on rTMS treatment in patients with OCD. First, the mechanism of action is discussed, followed by the efficacy and side effects of rTMS at various brain targets, and finally implications for the future. Due to the lack of studies with comparable stimulation or treatment parameters and with reliable designs, it is difficult to draw clear conclusions. In general, rTMS appears to be effective in open-label studies; however, this has not yet been replicated in randomized, sham-controlled trials.

KeywordsRepetitive transcranial magnetic stimulation rTMS Treatment refractory Obsessive-compulsive disorder Targets  Download fulltext PDF



Author: Rianne M. Blom - Martijn Figee - Nienke Vulink - Damiaan Denys

Source: https://link.springer.com/







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