Algorithm for the early diagnosis of vitamin b12 deficiency in elderly people Report as inadecuate




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Ricardo Sola ; Laura Barrios ; Klaus Pietrzik ; Manuel J. Castillo ; Marcela González-Gross ;Nutrición Hospitalaria 2013, 28 5

Author: Gonzalo Palacios

Source: http://www.redalyc.org/articulo.oa?id=309230208011


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Nutrición Hospitalaria ISSN: 0212-1611 info@nutriciónhospitalaria.com Grupo Aula Médica España Palacios, Gonzalo; Sola, Ricardo; Barrios, Laura; Pietrzik, Klaus; Castillo, Manuel J.; González-Gross, Marcela Algorithm for the early diagnosis of vitamin B12 deficiency in elderly people Nutrición Hospitalaria, vol.
28, núm.
5, septiembre-octubre, 2013, pp.
1447-1452 Grupo Aula Médica Madrid, España Available in: http:--www.redalyc.org-articulo.oa?id=309230208011 How to cite Complete issue More information about this article Journals homepage in redalyc.org Scientific Information System Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Non-profit academic project, developed under the open access initiative 12.
ALGORITHM_01.
Interacción 24-10-13 12:30 Página 1447 Nutr Hosp.
2013;28(5):1447-1452 ISSN 0212-1611 • CODEN NUHOEQ S.V.R.
318 Original - Ancianos Algorithm for the early diagnosis of vitamin B12 deficiency in elderly people Gonzalo Palacios1, Ricardo Sola2,3, Laura Barrios4, Klaus Pietrzik5, Manuel J.
Castillo2 y Marcela González-Gross1,2 1 ImFINE Research Group.
Department of Health and Human Performance.
Faculty of Physical Activity and Sport SciencesINEF.
Universidad Politécnica de Madrid.
Spain.
2EFFECTS 262 Group.
Department of Physiology.
Faculty of Medicine. Universidad de Granada.
Spain.
3Department of Hematology.
Hospital Clínico Universitario San Cecilio.
Granada.
Spain. 4 Centro Técnico de Informática.
CSIC.
Madrid.
Spain. Abstract Background: The elderly population is particularly at risk for developing vitamin B12-deficiency.
Serum cobalamin does not necessarily reflect a normal B12 status.
The determination of methylmalonic acid is not available in all laboratories.
Issues of sensitivity for holotranscobalamin and the low specificity of total homocysteine limit their utility.
The aim of the present study is to establish a diagnostic algorithm by using a combination of these markers in pl...





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