Crystallization via tubing microfluidics permits both in situ and ex situ X-ray diffractionReport as inadecuate




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1 CINaM - Centre Interdisciplinaire de Nanoscience de Marseille 2 Institut de Recherches Servier 3 SSOLEIL - Synchrotron SOLEIL

Abstract : We used a microfluidic platform to address the problems of obtaining diffraction quality crystals and crystal handling during transfer to the X-ray diffractometer.
We optimize crystallization conditions of a pharmaceutical protein and collect X-ray data both in situ and ex situ.






Author: Charline Gerard - Gilles Ferry - Laurent Vuillard - Jean A Boutin - Léonard Chavas - Tiphaine Huet - Nathalie Ferte - Romain Gro

Source: https://hal.archives-ouvertes.fr/



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