Adults with corrected oesophageal atresia: is oesophageal function associated with complaints and-or quality of lifeReport as inadecuate




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Pediatric Surgery International

, Volume 24, Issue 5, pp 537–541

First Online: 20 March 2008Accepted: 27 February 2008

Abstract

The aim of this study was to evaluate oesophageal function after correction of oesophageal atresia in adults, and to investigate the association between complaints, oesophageal function and quality of life QoL. Twenty-five adults were included who participated in previous follow-up studies, during which complaints of dysphagia and gastro-oesophageal reflux GOR, results of upper gastrointestinal endoscopy, oesophageal biopsies and QoL had been collected. Manometry was performed in 20 patients, 24 h pH-measurements were performed in 21 patients. pH-values sample time 5 s were calculated using criteria of Johnson and DeMeester. Associations were tested with ANOVA and χ-tests. Ten patients 48% reported complaints of dysphagia, seven 33% of GOR. The amplitude of oesophageal contractions was low <15 mmHg in four patients 20%. pH-measurements showed pathological reflux in three patients 14%. Patients reporting dysphagia more often had disturbed motility P = 0.011, and lower scores on the domains -general health perceptions- SF-36 P = 0.026 -standardised physical component- SF-36 P = 0.013, and -physical well-being- GIQLI 0.047. No other associations were found. This study shows a high percentage of oesophageal motility disturbances and a moderate percentage of GOR after correction of oesophageal atresia. Patients reporting dysphagia, whom more often had disturbed motility, seemed to be affected by these symptoms in their QoL.

KeywordsOesophageal atresia Long-term follow-up Manometry pH-measurements Quality of life  Download fulltext PDF



Author: J. A. Deurloo - E. C. Klinkenberg - S. Ekkelkamp - H. A. Heij - D. C. Aronson

Source: https://link.springer.com/article/10.1007/s00383-008-2120-1







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