Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal CancerReport as inadecuate




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Case Reports in Oncological MedicineVolume 2014 2014, Article ID 203027, 6 pages

Case Report

Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 2240, Republic of Korea

Department of Radiology, Ilsan Paik Hospital, Inje University College of Medicine, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 2240, Republic of Korea

Received 11 November 2013; Accepted 2 January 2014; Published 4 March 2014

Academic Editors: K. Jamil, D. V. Jones, and L. Lu

Copyright © 2014 Ji Hoon Choi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Acute lung injury occasionally occurs after chemotherapy, but pulmonary toxicities by oxaliplatin-based chemotherapy have rarely been identified. A 76-year-old female with rectosigmoid colon cancer presented with ongoing dyspnea after the eighth cycle of standard chemotherapy 5-fluorouracil, sodium folinic acid, and oxaliplatin: FOLFOX. Nodular consolidation progressed despite antibiotics and BAL fluid analysis was compatible with the diagnosis of sarcoidosis. Corticosteroid therapy rapidly improved the symptoms and radiographic findings. We report this first case of secondary sarcoidosis related to FOLFOX therapy with review of references.





Author: Ji Hoon Choi, Jung A. Shin, Hye Kyeong Park, Su Young Kim, Hoon Jung, Sung-Soon Lee, Hye Ran Lee, and Hyeon-Kyoung Koo

Source: https://www.hindawi.com/



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